research journals and reports on vitamins and supplements

SYSTEM BIOLOGY

Systems biology of personalised nutrition

Personalized nutrition is here to stay, and more information on metabolic processes in the areas of nutrition and health is becoming available for use in personalized nutrition.

system_biology.2 ARTICLE ON VITAMINS AND MINERALS system_biology.2 ARTICLE ON VITAMINS AND MINERALS

Different needs for different athletes

The article outlines the different nutritional needs for different athletes, highlighting a personalised nutrition approach must extend beyond professional athletes but also to everyone engaged on physical exercise.

Engage with our bodies needs

By ensuring that we engage with our bodies true needs, we can then begin to understand what our bodies nutritional needs are and then supplement for this.

Vitamin D and Systems Biology

The study reviews current evidence on specific nutrients, like vitamins D, C, zinc, and selenium, emphasizing their roles in immune health. Findings suggest that while these supplements can support immune responses, excessive intake may be counterproductive. The authors encourage further research to determine optimal dosages for enhancing immunity without adverse effects.

Varying calcium needs and your true requirements

The paper describes the adverse effects of chronic exposure to high calcium intakes are an increase in the prevalence of kidney stones and hypercalcemia.

Biomarkers in nutritional epidemiology: applications, needs and new horizons

By examining population genetics and gene-environment interactions, the article emphasizes the potential for personalized medicine, where treatments could be tailored based on individual genetic profiles.

PERSONALISED NUTRITION

The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition

The article addresses concerns with overuse of supplements by firstly understanding what levels of personalisation is required, identifying different sub groups that can have less or more .effectiveness from personalised nutrition and supplements.

Effect of personalized nutrition on health-related behaviour change: evidence from the Food4Me European randomized controlled trial

The main findings of this study were that, overall, Personal Nutrition advice was more effective in improving dietary behaviours when compared with conventional ‘one size fits all’ population-based advice.

The balance between food and dietary supplements in the general population

Supplements continue to be used by an increasing proportion of the population, so their contribution to diet, health and disease needs to be monitored

Differing the needs between different athletes

The article outlines the different nutritional needs for different athletes, highlighting a personalised nutrition approach must extend beyond professional athletes but also to everyone engaged in physical exercise.

Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth

The benefits of personalised nutrition are relevant to the individuals needs based on their environment, lifestyle and biology makeup. Understanding these can then cater to unique individual needs, ensuring better health outcomes and sustained performance.

Personalising nutritional guidance for more effective behaviour change

The benefits of personalised nutrition have long been studied. The study from Cambridge University in 2014 suggests behaviour change techniques (BCT’s) must be incorporated to understand more about ones health and how to optimise it.

ARE YOU OVERUSING?

Vitamin D overuse

Very high levels of vitamin D in your blood (greater than 375 nmol/L or 150 ng/mL) can cause nausea, vomiting, muscle weakness, confusion, pain, loss of appetite, dehydration, excessive urination and thirst, and kidney stones. Extremely high levels of vitamin D can cause kidney failure, irregular heartbeat, and even death. High levels of vitamin D are almost always caused by consuming excessive amounts of vitamin D from dietary supplements.

Vitamin A overuse

Excessive Dietary Intake of Vitamin A Is Associated with Reduced Bone Mineral Density and Increased Risk for Hip Fracture

Multivitamin-multimineral supplements’ effect on total nutrient intake

Research showed multivitamin users were also more likely to have potentially excessive intakes, particularly for iron, zinc, vitamin A, and niacin.

Multivitamin-multimineral supplements' effect on total nutrient intake

Intakes from foods plus multivitamins were at risk of being excessive for >15% of the participants in vitamin A, niacin, and folate.

Dietary Reference Intakes for Calcium and Vitamin D

The adverse effects of chronic exposure to high calcium intakes are an increase in the prevalence of kidney stones and hypercalcemia. Although ensuring adequacy is important, there is now an emerging issue of excess vitamin D intakes

Vitamin D overuse

Taking too many vitamin D supplements over a long period of time can cause too much calcium to build up in the body (hypercalcaemia). This can weaken the bones and damage the kidneys and the heart.

Toxicology of Micronutrients: Adverse Effects and Uncertainty

Pyridoxine (B6) illustrates the problems that can arise when vitamins are used at very high doses for the treatment of clinical conditions.

Exploring GP and patient attitudes towards the use and deprescribing of dietary supplements: a survey study in Switzerland

Research carried out in Swiss GPs showed that “Swiss GPs were unaware of many dietary supplements used by their older patients, which may affect medication optimisation efforts”, suggesting a need to understand a patients needs further.

OUR GRANULES

Optimising the composition of the ratio of alpha- to gamma- tocopherol in vitamin E

The study showed that through the substitution with a new formula of the product vitamin E, both the alpha and gamma tocopherol content in the plasma increased significantly. The ratio of alpha to gamma tocopherol thereby shifted in favour of tocopherol at a ratio of around 28:1.

Effects of mixed tocopherols versus a-tocopherol on nuclear factor kappa B activation in mononuclear leukocytes of healthy male volunteers

These data demonstrates for the first time that mixed tocopherols exert a protective effect on NF kB activation in smokers.

Influencing the serum levels of the vitamins B12, folic acid and vitamin D3 through individualised versus standard supplementation with micronutrients in overweight adults

The study showed great benefits that a targeted supplementation of individualised micronutrients based on laboratory data leads to better levels of vitamin B12, folic acid and D3 in the blood compared to standardised supplementation.

Effects of individual micronutrient prescriptions on specific laboratory parameters in supportive cancer treatment

Taking individually adapted micronutrient supplements as part of a supportive therapy led to an intended improvement of specific laboratory values that represent the antioxidative states and systemic inflammation.

Further literature about our guar gum used as a carrier substance

• The guar gum we use is of a controlled, certified and highly purified quality.

• Its water-binding property is 8 to 10 times greater than that of wheat bran.

• Guar is a pure fibre, difficult to digest – if at all – and water-soluble.

• Guar binds unwanted cholesterol, bile acid and harmful substances in the small intestine and eliminates them from the body through the large intestine and stool.

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